Fibromyalgia is a long-term condition that involves widespread body pain. The pain happens along with fatigue. It also can involve issues with sleep, memory and mood. Researchers think that fibromyalgia affects the way the brain and spinal cord process painful and nonpainful signals. That increases your overall sensitivity to pain. Symptoms often start after a triggering event. Triggers can include injuries, surgery, infections or emotional stress. Or the symptoms can build up over time, with no single event to trigger them. Women are more likely to get fibromyalgia than are men. Many people who have fibromyalgia also have: Headaches. Jaw and facial pain due to temporomandibular joint (TMJ) disorders. Irritable bowel syndrome. Anxiety. Depression. There's no cure for fibromyalgia. But medicines and other treatments can help control the symptoms. Exercise, talk therapy and techniques that lower stress also may help.